In hemorrhagic stroke, increased intracranial pressure can cause which effect on brain tissue?

In hemorrhagic stroke, increased intracranial pressure can cause which effect on brain tissue?

• A. Increased metabolism and improved oxygenation
• B. Decreased metabolism and hypoxia
• C. No change in brain metabolism
• D. Increased perfusion of brain tissue

Answer: (B)

When intracranial pressure rises, cerebral perfusion pressure falls because CPP = MAP − ICP. That drop means less blood reaches brain tissue, so oxygen delivery decline leads to hypoxia. Brain cells rely on oxygen for energy; with less oxygen, ATP production drops and cellular metabolism slows. So tissue becomes hypoxic and metabolism decreases, which is the expected response to reduced blood flow from high ICP. The other options imply more blood flow or no change, which isn’t consistent with the impaired perfusion caused by elevated ICP.

When intracranial pressure rises, cerebral perfusion pressure falls because CPP = MAP − ICP. That drop means less blood reaches brain tissue, so oxygen delivery decline leads to hypoxia. Brain cells rely on oxygen for energy; with less oxygen, ATP production drops and cellular metabolism slows. So tissue becomes hypoxic and metabolism decreases, which is the expected response to reduced blood flow from high ICP. The other options imply more blood flow or no change, which isn’t consistent with the impaired perfusion caused by elevated ICP.